קורות חיים – CV

RESUME
13.4.2013

  1. PERSONAL DETAILS

Name: Uri Rosenschein, M.D.

Contact  Mr.  Rosenschein here

e-mail: uri.rosenschein@b-zion.org.il

Date and Place of Birth: 6.9.1953, Buenos Aires, Argentina

Military Service: 1971-1973

Captain

Decoration of Valor 1973

Marital Status: Married + 3

  1. ACADEMIC DEGREES

I Medicine

1973-1979 Sackler School of Medicine

Tel Aviv University

II Management

2000 – 2002 Kellogg-Recanati Executive MBA

Tel Aviv University
Northwestern University

  1. ACADEMIC APPOINTMENTS

1995-2005 Senior Lecturer Faculty of Medicine ,Tel Aviv University.

2005-present Associated Professor Faculty of Medicine-Technion.

  1. PROFESSIONAL EXPERIENCE

Period Institution/Organization Department Rank/Function

1980-1981 Tel Aviv Medical Center

Sackler School of Medicine Internship

1981-1984 Meir General Hospital Internal Resident

Sackler School of Medicine Medicine B

1985-1988 Meir General Hospital Cardiology Fellow

Sackler School of Medicine

1988-1989 College of Physicians & Echocardiography Fellow

Surgeons, Cardiac &

Columbia University. Catheterization Fellow

1990-1991 The University of Michigan Interventional Fellow

Hospitals. University of Cardiology

Michigan.

1992-2003 Tel Aviv Medical Center Cardiology Attending

Sackler School of Medicine Physician

2003-Present Bnai-Zion Medical Center Cardiology Director

Haifa, Israel Department

  1. RESEARCH INTERESTS

1. Therapeutic applications of ultrasound

2. Interventions in acute myocardial infarction

3. Thrombectomy and embolic protection devices

4. Biology of acute coronary syndromes

  1. TEACHING EXPERIENCE

Courses

  1. 2000 – Established the course & curriculum for the training of cardiac

catheterization teams for the Working Group For Interventional

Cardiology.

  1. 2001- 2004 Interventional Cardiology

Post graduate Cardiology Course

Sackler School of Medicine.

  1. 2007- 2008 Introduction to Clinical Medicine course

Cardiac Catheterization and Coronary Interventions,

The Ruth & Bruce Rappaport, Faculty of Medicine, Technion.

  1. 2008 – Present Technology Development & Enterprising ,Course Director, The Ruth & Bruce Rappaport, Faculty of Medicine, Technion.
  1. 2011- Establish curriculum of Cardiology

The Ruth & Bruce Rappaport, Faculty of Medicine, Technion.

Clerkships:

  1. 1991-2002 Routine teaching of cardiology to students & residents in

the Department of Cardiology, Tel Aviv Medical Center.

  1. 2003-2011 Supervising the teaching program and active participation

in teaching and training of students and residents in the Department

of Cardiology, Bnai-Zion Medical Center.

The Ruth & Bruce Rappaport, Faculty of Medicine, Technion.

  1. TECHNION ACTIVITIES

1. Course Director 2008-Present Technology Development & Enterprising

The Ruth & Bruce Rappaport, Faculty of

Medicine, Technion.

2. Chairman of Cardiology 2010 – Present

3. Vice Dean, The Ruth & Bruce 2011 – Present

Rappaport, Faculty of Medicine,

Technion.

  1. PUBLIC PROFESSIONAL ACTIVITIES

1990 – 2001 Founder, Chief Medical Officer

Angiosonics Ltd.

1999 – 2001 General Secretary
The Working Group for Interventional Cardiology
The Israeli Society of Cardiology

2000 – 2005 The Nucleus Working Group on Coronary

Intervention

European Society of Cardiology

2001- Present Co-Founder, The Yearly cardiology debate meeting "Point Counter Point".

2006- Present Founder, Chief Medical Officer

Gardia Ltd.

2006 – 2008 Director

CMT Ltd.

Reviewer Circulation

Journal American College of Cardiology

Catheterization and Cardiovascular Intervention
Journal of Endovascular Therapy

GIF

Israel Academy of Science
BSF International Journal of Cardiovascular Intervention.

Guest editor Seminars in Interventional Cardiology (2002)

Consultant TEVA Pharmaceutics

Medinol.

  1. MEMBERSHIP IN PROFESSIONAL SOCIETIES

National

1992 – present Israel Heart Society

1997 – present The Working Group for Interventional Cardiology

International

1990 – present American college of Cardiology Fellow

1992 – present The Society for Cardiac Angiography Fellow

and Interventions

2001 – present European Society of Cardiology Fellow

  1. HONORS

1988 Israel Board of Cardiology Award of Excellence

  1. The Kellerman Young Investigator Prize
  1. GRADUET STUDENTS

PhD

1. 2000-2004 Frida Klein

Ph.D

Co-Supervision w/ Prof S. Grossman, Bar Ilan University

Title : Pathways controlling the apoptotic process in human malignant

lymphoid cells exposed to therapeutic ultrasound.

Grade: Cum Laude

2. 2000-2004 Liron Shemesh

Ph.D

Co-Supervision w/ Prof H. Breitbart , Bar Ilan University

Title: Induction of apoptosis in human cancer cells exposed to therapeutic

ultrasound: Determination of the apoptotic pathways.

Grade: Cum Laude

MD Thesis

1. 2005 Guy Rofe

MD Thesis

Faculty of Medicine, Technion

Title: Coronary Flow Patterns after Primary PCI in AMI Patients.

Grade: Cum laude

2. 2006 Ofer Kobo

MD Thesis

Faculty of Medicine, Technion

Screening, diagnosis and treatment of Renal Artery Stenosis by PTRA with

stenting.

Basic Science

1. 2002-2003 Roi ilan

Basic Science Thesis

The Scientific Council of the Israel Medical Association

Title: Enhancement of myocyte gene trasfection with the use of therapeutic

ultrasound

  1. RESEARCH GRANTS

1987 – 1988 US-Israel Binational Industrial

Research and Development Foundation $36,000

1991 – 1993 Abbot Laboratories $10,000

1993 – 1996 Joint German-Israeli Research Program DM 261.000

1996 – 2001 Angiosonics Inc $250,000

  1. SIGNIFICANT PROFESSIONAL PROJECTS.

1. 1990 – 2001 Conception followed by R&D on the biological effects of

ultrasound (high power, low frequency) followed by technology development

for ultrasound thrombolysis followed by animal studies, First in Man study,

"Live Case" at prestigious meetings (TCT 1999) and CRT in the US

under the FDA.

2. 2007- Present Conception followed by development of embolic protection

device to be used during interventional procedures. Technology development

was followed by animal studies and First Man study, "Live Case" at prestigious meetings (TCT & LINC 2010). Multicenter trial design has been finalized and clinical trial for Carotid Stenting under the FDA will start soon. Currently a multicenter registry in SVGs is underway in Israel.

3. Principal Investigator in Multicenter International Trials-

2004-2005 EVOLVE

2004-2005 ACCLAIM 0202

    1. TIMI 36-(No 1 Recruiter world wide)
    1. TIMI 38

2007-2008 VENT-HEFT

2007-20011 HORIZONS

2006- Ongoing IMPROVE IT

2006- 2010 TIMI 42

2007- 2010 PLATO

2007- 2010 EARLY ACS-(Top 10 Recruiter world wide)

2008-Ongoing BLAST

2008-2011 TRACER

2009-2012 DAL

2009-2011 ALPHEE

2009-2011 KAI

2009-2011 BOREALIS

2010-2011 ACT V

2010-Ongoing TAO

2010-2013 GARDIA

2012-Ongoing RIVER PCI

2012-Ongoing PRESERVATION

2012-Ongoing SYMPLICITY

2013- Ongoing ACSIS

  1. PUBLICATIONS

Refereed papers in professional journals:

  1. Basic research (Hypothesis-driven
  1. Rosenschein U, Radnay J, Shoham D, Shainberg A, Klajman A, Rozenszajn LA.
    Human muscle-derived, tissue specific, myocytotoxic T-cell lines in dermatomyositis.
    Clin Exp Immunol, 1987; 67:309-318.
  1. Rosenschein U, Bernstein J, DiSegni E, Kaplinsky E, Bernheim J, Rozenszajn LA.
    Experimental ultrasonic angioplasty: disruption of atherosclerotic plaques and thrombi in vitro and arterial recanalization in vivo.
    J Am Coll Cardiol, 1990;15:711-717.
  1. Rosenschein U, Lenz R, Radnay J, Ben-Tovim T, Rozenszajn LA.
    Streptokinase immunogenicity in thrombolytic therapy for acute myocardial infarction.
    Isr J Med Sci, 1991;27:541-545.
  1. Rosenschein U, Ellis SG, Yakubov SJ, Haudenschild CC, Dick RJ, Topol EJ.
    Histopathologic correlates of coronary lesion angiographic morphology: lessons from a directional atherectomy experience.
    Coronary Artery Disease,1991;3:953-961.
  1. Rosenschein U, Rozenszajn LA, Kraus L, Marboe CC,

Watkins JF, Rose EA, David D, Cannon JP, Weinstein JS.

Ultrasonic angioplasty in totally occluded peripheral arteries:

initial clinical, histologic and angiographic results.
Circulation, 1991;83:1976-1986.

6. Det Wiler P, Watkins JF, Rose EA, Ratner A, Rosenschein U.
Mechanical and acoustic analysis in ultrasonic angioplasty.
Diagnostic and Therapeutic Cardiovascular Interventions, George

S. Abela, M.D. Editor.

Proc. SPIE, 1991;1425:149-155.

7. Rosenschein U, Yakubov SJ, Guberinich D, Bach DS, Sonda PL,

Abrams GD, Topol EJ.
Shock wave thrombus ablation: a new method for noninvasive

mechanical thrombolysis.
Am J Cardiol, 1992;70:1358-1361.

8. Bach DS, Armstrong WF, Erbel R. Ellis SG, Sousa J, Rosenschein U.

Ultrasound detection of cavitation as a phenomenon common to

intervention devices causing tissue ablation.
Diagnostic and Therapeutic Cardiovascular Interventions, George S.

Abela, M.D., Editor.

Proc .SPIE 1992;1624:224-228.

9. Hartnell, GG, Saxton JM, Friedl SE, Abela GS, Rosenschein U.

Ultrasonic thrombus ablation: in vitro assessment of a novel device

for intracoronary use.
J Interven Cardiol, 1993;6:69-76.

10. Rosenschein U, Frimerman A, Laniado S, Miller HI.
Study of the mechanism of ultrasound angioplasty from human

thrombi and bovine aorta.
Am J. Cardiol, 1994;74:1263-1266.

11. Rosenschein U, Ellis SG, Haudenschild CC, Yakubov SJ, Muller

DWM, Dick R, Topol EJ.
Comparison of histopathologic coronary lesions obtained from

directional atherectomy in stable angina versus acute coronary

syndromes.
Am J Cardiol, 1994;73:508-510.

12. Roth A, Eshchar Y, Keren G, Kerbel S, Harsat A, Villa Y, Laniado S, Miller HI

The Ichilov Magnesium Study Group. Effect of magnesium on restenosis

after percutaneous transluminal coronary angioplasty: a clinical and

angiographic evaluation in a randomized patient population – a pilot study.

Eur Heart J, 1994;15:1164-1173.

13. Rosenschein U, Rozenszajn LA, Bernheim J, Keren G, Alter A,

Frimerman A, Laniado S, Roth A, Miller H.
Safety of coronary ultrasound angioplasty: effects of sonication on

intact canine coronary arteries.
Cathet Cardiovasc Diagn, 1995;35:64-71.

  1. Roth A, Eshchar Y, Keren G, Kerbel S, Harsat A, Villa Y, Laniado S, Miller HI

and the Ichilov Magnesium Study Group.
Effect of magnesium on restenosis after percutaneous transluminal coronary

angioplasty: a clinical and angiographic evaluation in a randomized patient

population – a pilot study.
Eur Heart J, 1994;15:1164-1173.

  1. Alter A, Rozenszajn LA, Miller HI, Rosenschein U.
    Ultrasound inhibits the adhesion and migration of smooth muscle

cells in vitro.
Ultrasound in medicine and biology, 1998; 24:711-721.

  1. Ashush H, Rozenszajn LA, Blass M, Barda-Saad M, Azimov D, Zipori D, Rosenschein U.
    Apoptosis induction of human myeloid leukemic cells by ultrasound exposure.
    Cancer Res, 2000;60:1014-1020.
  1. Rosenschein U, Furman V, Kerner E, Fabian I, Bernheim J, Eshel Y.
    Ultrasound imaging-guided non-invasive ultrasound thrombolysis: pre-clinical results
    Circulation, 2000;102: 238-245.
  1. L.A.Rozenszajn, L. Shemesh-Darvish, R. Elimelech, J. Radnay,

F. Firestein,and U. Rosenschein.

Induction of Apoptosis by Ultrasound Application in Human Mlignant

Lymphoid Cells:Role of Mitochondria-Caspase Pathway Activation.

Annals of The New York Academy of Sciences, 2003;1010.

  1. Singh M, Rosenschein U, Kalon KH, Berger PB, Kuntz R, Holmes DR

Treatment of Saphenous Vein Bypass Grafts with Ultrasound Trombolysis: A

Randomized Trial (ATLAS)

Circulation 2003;107:2331-2336.

20. Schafer S, Kliner S , Klinghammer L,Kaarmann H, Lucic I,Nixdorff

U, Rosenschein U , Werner G.Daniel,

F. A. Flachskampf.

Influence of Ultrasound Operating Parameters on Ultrasound-Induced

Thrombolysis in Vitro.

Ultrasound in Med & Biol. 2005:31;841-847.

21. E. Goldhammer, A. Tanchilevitch, I. Maor, Y. Biniamini, Rosenschein U,

M. Sagiv.

Exercise Training Modulates Cytokines Activity in Coronary Heart

Disease Patients.

Year Book of Sports Medicine (Mosby Editors).2006;211-213.

22. Sharif D, Rofe G, Sharif-Rasslan A, Goldhammer E, Makhoul N, Shefer

A, Hassan A, Rauchfleisch S, Rosenschein U.

Analysis of serial coronary artery flow patterns early after primary

angioplasty:new insights into the dynamics of the microcirculation.

IMAJ 2008;10(6):440-44.

23. Sharif D, Sharif-Rasslan A, Shahla C, Rosenschein U.

Application of Mitral Annular Systolic Displacements and Velocities for

the Evaluation of Left Ventricular Systolic Function and Reserve.

Cardiol 2011;2 (1):36-41

2. Clinical Descriptive Research

1. DiSegni E, Bakst A, Levi A, Rosenchein U, Klein Z, Beker B, Dean H, Kaplinksy E.
Percutaneous balloon valvuloplasty for calcific aortic stenosis in the elderly.

Harefuah, 1988; CXIV: 268-273.

2. DiSegni E, Bakst A, Levi A, Rosenchein U, Klein HO.
The mechanism of the obstruction in calcific aortic stenosis

with bicuspid aortic valve.
Cardiology, 1989; 76:450-454.

3. Nath FC, Muller DWM, Ellis SG, RosenscheinU, Chapekis A, Quain L, Zimmerman C, Topol EJ.
Thrombosis of a flexible coil coronary stent: frequency, predictors and clinical outcome.
J Am Coll Cardiol, 1993; 21:622-627.

4. Nath CF, Muller DWM, Rosenschein U, Ellis SG, Topol EJ.
Heparin monitoring during coronary interventions: activated

clotting time versus activated partial thromboplastin time.
Canad J Cardiol, 1993; 9: 797-801.

5. Shapira I, Frimerman A, Rosenschein U, Roth A, Keren G,

Laniado S,Miller HI.
Percutaneous transluminal coronary angioplasty in elderly

patients.
Cardiology, 1994; 85:88-93.

  1. Hartnell GG, Abela GSA, Rosenschein U.
    Thrombectomie par ultrasons: quelles utilisations intra-vasculaire et intra-coronaire?
    Le Mouvement Cardio Vasculaire, 1995;211-214.
  1. Lincoff AM, Topol EJ, Califf RM, Sigmon KN, Lee KL, Ohman M, Rosenschein U, Ellis SG.
    Significance of a coronary artery with thrombolysis in myocardial infarction grade 2 flow “patency” (outcome in the thrombolysis and angioplasty in myocardial infarction trials).
    Am J Cardiol, 1995;75:871-876.
  1. Roller M, Miller HI, Laniado S, Rosenschein U.
    Coronary ultrasound angioplasty – an update of an expanding technology.
    J Interven Cardiol, 1995; 8(6): 671-675.
  1. Rosenschein U, Topol EJ.
    Uncoupling clinical outcomes and coronary angiography: a review and perspective of recent trials in coronary artery disease.
    American Heart Journal, 1996;132: 910-920.
  1. Rosenschein U, Roth A, Rassin T, Bassan S, Laniado S, Miller HI.
    Analysis of coronary ultrasound thrombolysis endpoints in acute myocardial infarction (ACUTE Trial): results of the feasibility phase.
    Circulation, 1997; 95:1411-1416.
  1. Rosenschein U, Budde-Schwartzman B.
    Koronare ultraschallangioplastie: Standpunkt und neue klinische aspekte
    Herz, 1997;22:308-17.
  1. Brosh D, Miller HI, Hertz I, Laniado S, Rosenschein U.
    Ultrasound angioplasty: An Update Review
    Int J Cardiovasc Interventions, 1998;1:11-18.
  1. Rosenschein U.
    Ultrasound thrombolysis- an alternative to the pharmacologic approach.
    J Interven Cardiol, 1998;11:603-607.
  1. Rosenschein U, Gaul G, Erbel R, Amann F, Velasguez D, Stoerger H, Simon R, Gomez G, Troster J, Bartorelli A,Pieper M, Kyriakidis Z,Laniado S, Miller HI, Fajadet J.
    Percutaneous Transluminal Therapy of Occluded Saphenous Vein Grafts: Can the Challenge be met with Ultrasound Thrombolysis?
    Circulation, 1999; 99: 26-29.
  1. Blum A, Porat R, Rosenschein U, Keren G, Roth A, Laniado S, Miller HI.
    Clinical and inflammatory effects of dietary L-arginine in patients with intractable angina pectoris.
    Am J Cardiol, 1999;83(10):1488-90.
  1. Frimerman A, Miller HI, Siegal RJ, Rosenschein U, Roth A, Keren G.
    Intravascular ultrasound imaging of myocardial-infarction-related arteries after percutaneous transluminal coronary angioplasty reveals significant plaque burden and compensatory enlargement.
    Int J Cardiovasc Interventions, 1999;2:101-107.
  1. Viskin S, Brosh D, Rosenschein U, Barron HV.
    Prevention of cardiac arrest: risk assessment after myocardial infarction.
    Cardiac Electrophysiol Rev, 1999;3:20-23
  1. Brosh D, Rosenschein U.
    Catheter-Based Ultrasound Thrombolysis – A New Promising Thrombus-Debulking Device for the Treatment of intracoronary Thrombosis
    Semin Intervent Cardiol 2000;5:149-155
  2. Rosenschein U, Kuntz R.
    Treatment of Lesions with Thrombus:
    Beyond Stents and GP IIb/IIIa Inhibitors
    Semin Intervent Cardiol 2000;5:157-160.
  1. Rosenschein U, Brosh D, Halkin A.
    Coronary ultrasound thrombolysis: from acute myocardial infraction to saphenous vein grafts and beyond.
    Current Interven Cardiol Rep 2001;3:5-9.
  1. Halkin A, Rosenschein U.
    Catheter-Delivered Ultrasound Therapy for Native Coronary Arterial Thrombosis and Occluded Saphenous Vein Grafts.
    Echocardiography 2001; 8: 225-231.
  1. Brosh D, Bartorelli AL, Fajadet J, Cribier A, Mesa J, Calderon L, Martyn T, Amann F, Sampaolesi A, Desmet W, Rosenschein U for the Acolysis Registry Study Group.
    Percutaneous Transluminal Ultrasound Thrombolysis in Native Coronaries in the Setting of Acute Coronary Syndromes.

    Catheter Cardiovasc Interven , 2002;55:43-50.
  2. Halkin A, Rosenschein U, Barron HV, Viskin S.

Prevention of Cardiac Arrest:Risk Assessment after myocardial Infarction

Cardiac Electrophysiology Rev 2002;6(1-2):9-14.

  1. Topaz O, Perin EC, Jesse RL, Mohanty PK, Carr M, Rosenschein U

Power Thrombectomy in Acute Coronary Syndromes

Angiology. 2003;54:457-468.

  1. Halkin A, Holmes DR, Stone GW, Rosenschein U.

Percutaneous Treatment of Thrombus Rich Coronary Lesions: Beyond

Stents and GP IIb/IIIa Inhibitors.

IMAJ 2003; 5:795-800.

  1. Atar S, Rosenschein U. Perspectives on the Role of

Ultrasonic Devices in Thrombolysis.

Journal of Thrombosis and Thrombolysis. 2004;17(2):107-114.

  1. Goldhammer E., Tanchilevitch A, Rosenschein U, Maor I, Sagiv M, Beniamini Y.

Exercise training modulates cytokines activity in coronary heart disease patient.

Int J of Cardiology 2005;8(1):93-99.

  1. Bar-Meir E, Zeina AR, Blinder J, Rosenschein U.

Assessment of coronary artery bypass grafts by cardiac tomography angiography.

IMAJ 2005;7(4):275-6.

  1. Hatem H , Nabeel M, Amin H, Shefer A, Rosenschein U.

Embolic protection: Limitations of current technology and novel concepts.

Int J Cardiovasc Intervent. 2005;7(4):176-82

  1. Zeina AR, E Barmeir, J Blinder, Roseschein U.

Coronary Artery Imaging Using Cardiac CTA.

Harefuah. 2005;144(10):705-10

  1. Hatem H, Nabeel M, E Grenadir, F Kusniec, Rosenschein U.

Anchor Wire Technique Improves Device Deliverability during PCI of

CTOs and Other Complex Subsets.

Acute Cardiac Care. 2006;8:139-142.

  1. Zeina AR, Odeh M, Blinder J, Rosenschein U, Barmeir, E.

Myocardial Bridging: Evaluation on Multidetector-Computed

Tomography.

AJR, 2007;188(4):1069-1073.

33. Zeina AR, Blinder J, Sharif D, Rosenschein U, Barmeir E.

Congenital coronary artery anomalies in adults: non-invasive

assessment with multidetector computed tomography.

The British Journal of Radiology, 2009; 82:254-261.

34. Zeina AR, Sharif D, Blinder J, Rosenschein U, Barmeir E.

Noninvasive assessment of coronary artery ectasia using multidetector computed tomography.

Coronary Artery Disease 2007;18(3):175-180.

35. Zeina AR, Rosenschein U, Barmeir E.

Dimensions and anatomic variations of left main coronary artery in normal population:multidetector computed tomography assessment.

Coronary Artery Disease 2007;18(6):477- 482.

36. Goldhammer U, Biniamini Y, Maor I ,Rosenschein U, Lanir A.

The Early Anti-Oxidant Effect of Carvedilol Predicts Clinical Course in

Congestive Heart Failure Patients.

J. Cardiovasc Med 2007;8(6):453-456.

37. Zeina AR, Odeh M, Rosenschein U, Zaid G, Barmeir E.

Coronary artery disease among asymptomatic diabetic and nondiabetic

Patients undergoing coronary computed tomography angiography.

Coronary Artery Disease 2008;19 (1):37-41

38. Lubovich A, Rosenschein U

PCI vs CABG in Patients with Multivessel and Left Main Coronaries

Artery Disease:Lessons from the SYNTAX Trial.

Harefua Cardiology, 2009;7-9

39. Allah S , Rivlin Y , Shnizer S , Rosenschein U , Goldhammer E.

Serum oxidizability potential of ischemic heart disease patients is

associated with exercise test results and disease severity.

World Journal of Cardiology, 2009;31(1):46-50

40. Shanati A, Rivlin Y, Rosenschein U, Goldhammer E.

Oxidizability Potential IS Associated with Exercise Test Results and Coronary Artery Disease Severity in IHD Patients.

World J Cardiol 2009;1(1):26-30.

41. Goldhammer E, Rivlin Y, Shnizer S, Shanati A, Sagiv M, Rosenschein U.

Serum Oxidizability Potential is Associated with Age and Exercise Test

Results.

Eur Rev Aging Phys Act 2010;7:37-41.

42. Zaid G, Yehudai D, Rosenschein U, Zeina AR.

Coronary artery disease in an asymptomatic population undergoing a multidetector computed tomography (MDCT) coronary angiography.

The Open Cardiovascular Medicine Journal, 2010;4:7-13.

43. Kobo O, Hammoud M, Makhoul N, Hatem O, Rosenschein U.

Screening, diagnosis, and treatment of renal artery stenosis by

percutaneous transluminal renal angioplasty with stenting.

IMAJ 2010;12(3):140-143

44. E. Goldhammer, Y. Ben Moshe, A. Lubovich, Y. Rivlin, I. Maor, R. Zeina,

Rosenschein U.

Serum Endothelin-1, MMP-9, and Myeloperoxidase and Coronary Artery

Morphology as Detected by Multi-Slice CT Angiography in Intermediate

and High Risk Asymptomatic Subjects.

The Open Biomarkers Journal, 2010;3:7-12.

45. Lubovich A, Hatem H, Behar S, Rosenschein U.

Bypassing the Emergency Room to Reduce Door-to-Balloon Time and

Improve Outcomes of Patients with ST Elevation Myocardial Infarction:

The Acute Coronary Syndrome Israeli Survey Experience.

IMAJ 2011;13:216-219

46. Sharif D, Radzievsky N, Samniah N, Hassan A, Kushnir A, Rosenschein U.

Palpography Detects Mechanical Dyssnchrony and Worsens with Right

Ventricular Pacing and Reduced Left Ventricular Ejection Fraction.

PACE 2011;34(7):875-83

  1. Case Reports

1. Rosenschein U, Kuretz A, Schneider M, Klajman A.
Thrombocytosis and renal abscess.
Nephron 1998;48:246 (letter).

2. Rosenschein U, Ellis SG.
Pre-procedural warfarinization and brachial approach for elective coronary

stent placement – a possible strategy to decrease cost and duration of

hospitalization.
Catheterization and Cardiovascular Diagnosis, 1992; 25: 290-292.

3. Rassin T, Desmet W, Piessens J, Rosenschein U.
Ultrasound Thrombolysis in Stent Thrombosis.
Catheter Cardiovasc Interven 2000; 51: 332-334.

4. Zeina AR, Orlov I, Blinder J., Hassn A, Rosenschein U, Barmeir E.

Atypical Presentation of Acute Myocardial Infarction in a Young Man diagnosed by Multidetector Computed Tomography.

IMAJ 2006; 8(1):69-70.

5. Zeina AR, Zaid G, Sharif D, Rosenschein U, Barmeir E.

Huge Pericardial Hemangioma Imaging.

Circulation 2007;115:315-317.

  1. Zeina AR, Rosenschein U, Barmeir E.

Giant coronary-pulmonary artery fistula with multiple saccular

aneurysms: multidetector computed tomography evaluation.

Heart 2008;94:277

7. Zeina AR, Shefer A, Sharif D, Rosenschein U, Barmeir E.

Acute myocardial infarction in a young woman with normal coronary arteries and myocardial bridging.

The British Journal of Radiology, 2008;81(965):e141-4

8. Sharif D, Radzievsky N, Rosenschein U.

Recurrent Pericardial Constriction: Vibrations of the Knock, the

Calcific Shield, and the Evoked Constrictive Physiology
Circulation. 2008;118:1685-1688.

4. Review papers

1. Rosenschein U, Rassin T.
Ultrasound thrombolysis
Science & Medicine, January/February,1997; 36-43.

2. Elisha Bar-Meir, Abd-El-Rauf Zeina, Jorge Blinder, Rosenschein U.

Assessment of Coronary Artery Bypass Grafts by Cardiac Computed

Tomography Angiography.

IMAJ 2005;7:275-276.

5. Books and Book Chpters

1. Rosenschein U.

Ultrasound Angioplasty.

In: Strategic Approaches in Coronary Interventions. Eds: SG Ellis and DR Holmes.

Williams and Wilkins 1996: 150-158.

2. Agmon Y, Miller HI, Rosenschein U.

Ultrasound angioplasty using the angiosonics system.

In: Ultrasound Angioplasty. Ed: RJ Siegel.

Kluwer Academic Press.1996: 151-170.

3. Rosenschein U, Alter A, Rozenszajn LA.
Therapeutic ultrasound inhibits smooth muscle cells migration: a potential role in the prevention of restenosis.

In: Endoluminal Stenting. Ed: U Sigwart.

WB Saunders 1996: 129-133.

4. Rosenschein U.
Coronary ultrasound thrombolysis: state-of-the-art and clinical perspective. In: Strategic Approaches in Coronary Interventions. Eds: SG Ellis and DR Holmes. Williams and Wilkins 2000: 164-171.

Others

Images in Medicine

1. Rosenschein U.,MD, Kaganovitch N. MD, Machoul N. MD, Storch S. MD.

Treatment of Hypertension by Renal Artery Stenting.

IMAJ 2004; 6(7):445.

2. Zeina AR, J Blinder, Rosenschein,U. E Barmeir.

Coronary-pulmonary artery fistula diagnosed by multidetector computed tomography.

Postgraed.Med. J. 2006;82:15.

Editorials related to published manuscripts:

  1. Yock PG, Fitzgerald PJ. Catheter-based ultrasound thrombolysis: shake, rattle and reperfuse. Circulation 1997; 95:1360-1362.
  2. Holmes DR, Berger PB. Percutaneous revascularization of occluded vein grafts: is it still a temptation to be resisted?. Circulation 1999; 99: 8-11.
  1. de Feyter PJ. Percutaneous Treatment of Saphenous Vein Bypass Obstruction- A continuing obstinate problem. Circulation 2003;107:2285-2286

Meeting highlights” related to published manuscripts:

  1. Ferguson JJ. ACUTE Trial.

Circulation,1998, Vol 97,pp 1217-1220.

  1. Alexander JH, Kong DF, Cantor WJ. Highlights from the 71st American Heart Association Scientific Sessions: November 8 to 11,1998.
    Am Heart J 1999, Vol 137,pp 555-574.

Press release by professional societies (related to published manuscripts):

  1. Scientists employ sound method of dissolving clots in blood vessels.
    American Heart Association, March 1997.
  1. New Minimally Invasive Ultrasound Technique Restores Blood Flow in

Blocked Coronary Bypass Grafts.
European Society Cardiology, August 1998.

Interviewees by the American College of Cardiology(related topublished manuscripts):

1. American College of Cardiology (ACCEL)

Taped during the AHA

Washington, DC, November 13-17,1988

2. American College of Cardiology (ACCEL)

Taped during the AHA Anaheim CA, November 2001

(Vol. 54, No 2, Feb 2002)

Patents

1. 1989 In vivo Ultrasonic System for Angioplasty and Ultrasound

Contrast Imaging.

US Patent No. 5,163,421

2. 1992 Ultrasonic Transmission Apparatus
US Patent No 5,269,297

3. 1996 Ablation of blood thrombi by means of acoustic energy

US Patent No. 5,524,620

4. 1997 Method of inhibiting restenosis by applying ultrasonic energy.

US Patent No. 5,836,896.

5. 1997 Methods for prevention and treatment of

cancer and other proliferative diseases with

ultrasound energy.

US Patent No. 5,984,882

6. 1997 Ultrasound transmission apparatus and method of using same.
US Patent No. 5,971,949

7. 2000 Pulsed Mode Lysis Method

US Patent No. 6,113,558

8. 2009 Embolism Filter with Self-Deployable Guidewire Stop

US Patent No. 7,479,151 B2

9. 2007 Guidewire Stop

US Patent No. 7,819,844

11. 2009 Retrieval Catheter and Methods of Retrieving Deployed Medical

Devices.

US Patent No. 0254116-A1

12. 2009 Dual-Lumen Retrieval Catheters and Methods of Retrieving

Deployed Medical Device

US Patent No 2265223

13. 2009 Delivery Catheter with Constraining Sheath and Methods of

Deploying Medical Device Into a Body Lumen

US Patent No. 0254169-A1

  1. CONFERENCES

International

Plenary or invited talks

  1. Ultrasound Angioplasty.
    In: Application of New Coronary Devices Mini-course.
    The American College of Cardiology 42nd Annual Scientific Meeting, Anaheim, California. March 14, 1993.
  1. Ultrasonic Ablation of Intracoronary Thrombus.
    Transcatheter Cardiovascular Therapeutics.
    Washington DC. February 24-27, 1994.
  1. Ultrasound Thrombolysis.
    Transcatheter Cardiovascular Therapeutics.
    Washington DC. February 24-27, 1995.
  1. New Experience with Ultrasound Thrombolysis
    Moderne endovaskulare Katheterverfahren bei arteriellen Thrombosen.
    Munich, Germany, 1995.
  1. Analysis of coronary ultrasound thrombolysis endpoints in acute myocardial infarction (ACUTE Trial): results of the feasibility phase
    Transcatheter Cardiovascular Therapeutics.
    Washington DC. February 28 – March 3, 1996.
  1. Therapeutic Ultrasound in Cardiovascular Medicine – From Conception of Idea to Clinical Trial.
    1st European Workshop on Therapeutic Ultrasound Thrombolysis.
    Essen, Germany. May 18, 1996.
  1. Thrombolysis and Peripheral Thrombectomy
    Endovascular Therapy Course Coronary and Peripheral
    Paris, France, May 20-23, 1997
  1. The Dark Side of Coronary Stenting
    Endovascular Therapy Course Coronary and Peripheral
    Paris, France, May 20-23, 1997.
  1. PTCA and Acute MI: Tips and Tricks
    Endovascular Therapy Course Coronary and Peripheral
    Paris, France, May 20-23, 1997
  2. Therapeutic Coronary Ultrasound
    45th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand
  1. Melbourne, Australia, August 9, 1997.

Clinical studies in Coronary Ultrasound Thrombolysis
45th Annual Scientific Meeting of the Cardiac Society of Australia and New

Zealand Melbourne, Australia, August 9, 1997.

  1. Non-invasive ultrasound thrombolysis is safe and effective – in vitro

results Tran catheter Cardiovascular Therapeutics.
Washington DC. February 24-27, 1997.

13. The broad spectrum of ultrasonic angioplasty: a device for all seasons?

(thrombus, atheroma and total occlusions)
Transcatheter Cardiovascular Therapeutics.
Washington DC. February 24-27, 1997.

14. Coronary Ultrasound Thrombolysis – update
The 11th Annual Meeting of the Japanese Coronary Association,
Kobe, Japan. December 19-29, 1997.

15. Ultrasound Thrombolysis
7th Live Demonstration Course in Interventional Cardiology
Singapore, February 16-19, 1998.

16. Ultrasound
Myocardial reperfusion XI: concepts and controversies
Atlanta, Georgia, March 28, 1998

17. Thrombus-containing lesions
Endovascular Therapy Course
Paris, France May 5-8, 1998

18. Therapeutic ultrasound thrombolysis experimental results: methods and

analysis 10 Jahre Koronare Stentimplantation und Rotoblation in
Deutschland Essen, Germany, May 14-16, 1998.

19. Ultrasound thrombolysis: basic aspects of a novel concept
Nuove Modalita di Trattamento dei Trombi Coronarici
Milan, Italy, 12 June, 1998.

  1. Mechanical Coronary Thrombectomy: Ultrasound Atheroablation for Acute

MI’s (ACUTE study final results) and Thrombus-Containing SVG’s (ATLAS

update) Transcatheter Cardiovascular Therapeutics Washington DC, USA

October 1998.

21. Ultrasound Thrombolysis.
Myocardial reperfusion XII: concepts and controversies.
New Orleans, USA March 1999.

22. Lesions with Thrombus
American College of Cardiology 1999
New Orleans, USA March 1999.

23. An Update of Vascular Ultrasound Thrombolysis
Essener Gefasstage
Essen, Germany, June 1999.

24. Transcatheter ultrasound thrombolysis – from AMI to saphenous vein

grafts and beyond.
8th Annual Meeting of the Japanese Society of Interventional Cardiology
Yokohama, Japan July 1999

25. Ultrasound thrombolysis in AMI: The ACUTE and ATLAS Studies
Transcatheter Cardiovascular Therapeutics,
Washington DC, USA October 1999

26. Progress with ultrasound thrombolysis: interim observations from ATLAS
Transcatheter Cardiovascular Therapeutics,
Washington DC, USA October 1999

27. Transcatheter ultrasound thrombolysis – from AMI to saphenous vein

grafts and beyond 9th PTCA Live Demonstration Course Kurashiki, Japan,

February 2000

28. Current PCI in thrombus-rich lesions: facts and fantasies

9th PTCA Live Demonstration Course Kurashiki.

Japan, February 2000

29. Thrombus-containing lesions
American College of Cardiology 49th Annual Session (ACCIS2000)
Anaheim, CA, March 2000

30. eData Collection and Management in the eMillenium.
Vascular Interventions 2000 Milan, Italy, May 2000

31. Pathophysiology of PCI in intracoronary thrombosis
PCI in Thrombus Rich Lesions Symposium.

PCR Paris, France, May 2000

32. Devices avoid complications
2nd International Congress on Complications during Coronary Intervention:

Management and Prevention Lausanne, Switzerland, June 2000

33. Therapeutic ultrasound – Acolysis
Transcatheter Cardiovascular Therapeutics.
Washington DC October 17-21, 2000

34. The case for ultrasound thrombo-ablation in AMI intervention (Acolysis)
Transcatheter Cardiovascular Therapeutics.
Washington DC October 17-21, 2000

35. Ultrasound-induced apoptosis: implications for restenosis and cancer
2nd International Symposium on Sonodynamic Therapy
Yokohama, Japan, March 30, 2001

36. Therapeutic ultrasound can induce apoptosis in smooth muscle cells – a

potential role for restenosis prevention.
American College of Cardiology
Orlando, FL, March 18-21, 2001

37. Therapeutic ultrasound – possible role in coronary interventions – from,

thrombolysis to restenosis.
4th International Meeting on Interventional Cardiology: Frontiers in

Interventional Cardiology June 24-28, 2001.

38. External ultrasound for thrombolysis
In: Symposium entitled: Therapeutic Ultrasound – the new frontier
European Society of Cardiology
Stockholm, Sweden September 1-5, 2001

39. Aspirate or Dissolve: The challenges too mechanical treatment in primary

PTCA In: Symposium entitled: Optimal Reperfusion Strategies for Acute

Myocardial Infarction European Society of Cardiology Berlin, Germany

September , 2002.

40. My Worst Complications
Transcatheter Cardiovascular Therapeutics.
Washington DC, September, 2003

41. Using bioeffects of ultrasound for therapeutic purposes.

Euro-Echo Barcelona.

Spain, December,2003.

42. Embolic Protection Devices-Limitation Novel Ideas. 5th International Meeting on Interventional Cardiology: Frontiers in Interventional Cardiology. Tel-Aviv, Israel, December , 2003.

43. Therapeutic Ultrasound –The new frontier

Grand Rounds-Department of Cardiology University of Erlangen.

Erlangen, Germany, April 2004.

44. Therapeutic Ultrasound Past Present and Future Grand Rounds,

University of Essen.

Essen Germany. February 2005.

45. Cardiogenic Shock Revisited:Ongoing Frustration or New Hopes?

Innovations in Cardiovascular Interventions (ICI) Meeting.

Tel-Aviv, Israel, December 2006.

46. "Therapeutic ultrasound" Main Session on "New developments in

echocardiography and their clinical relevance".

73 Annual Scientific Meeting of the German Cardiac Society Mannheim,

Germany, April 2007.

  1. Use of extraction devices during primary percutaneous coronary intervention-prevention versus salvage approach.

PCR, Barcelona. Spain, May 2007

  1. The Gardia Concept Integrating Everyday Guidewires with A Modular Embolic Protection Device-In novative Devices and Futuristic Concepts II Non stent Based Technologies.

TCT, Washington DC ,October 2007.

  1. Bypassing the ER to Reduce DoortoBalloon Time the Israeli Experience-Interventional Strategies and Adjunct Pharmacology in ACS and AMI.

TCT, Washington DC ,October 2007.

  1. My Worst Complications coronary Intervention,

TCT, Washindgon DC,October 2007.

51. Perspectives on the role of ultrasound in clinical trials of thrombolysis

International Sonothrombolysis Conference,Mannheim,

Germany, July 2008.

  1. Embolic Protection and Thrombectomy-The GARDIA Embolic Protection

Device: Standard Guidewires Coupled to a Modular Filter.

TCT, Cardiovascular Therapeutics. Washington DC, October 2008.

  1. The Challenges in Embolic Protection

ICI Meeting, Tel-Aviv, December 2008.

  1. Ultrasound Thrombolysis – Waves, Bubbles and Clots.

The First D. Dan and Betty KahnUniversity of Michigan-Technion,

Collaborative Cardiovascular Research Symposium.

Ann Arbor, Michigan; October 4, 2011.

abstracts

  1. Mayevsky A, Zarchin N, Rosenschein U.
    The effect of anesthesia on the metabolic response to cortical spreading depression in the gerbil.
    Society for Neuroscience, Cincinnati, Ohio, Vol. 1, p. 261, 1981.
  1. Rosenschein U, Radnay J, Shoham D, Shainberg A, Klajman A, Rozenszajn LA.
    Tissue-specific T-lymphocytes in polymyositis.
    7th European Immunology Meeting, Jerusalem, Israel, p. 208, 1985.
  1. Rosenschein U, Bernstein J, Bakst A, DiSegni E, Kaplinsky E, Bernhein J, Rozenszajn LA.
    Ultrasonic angioplasty device: experimental in vivo thrombolysis and in vitro atherosclerotic plaque disruption.
    Circulation, Vol. 78(II), p. 270, 1988.
  1. Rosenschein U, Kraus L, Marboe CC, Bernstein J, Rozenszajn LA, Rose EA, Barr ML, Weinstein JS.
    Ultrasonic angioplasty: Initial clinical results in peripheral vascular disease.
    Circulation, Vol. 80(II), p. 306, 1989.
  1. Rosenschein U, Kraus L, Rozenszajn LA, David D, Marboe CC, Rose EA, Watkins JF, Weinstein JS.
    Clinical experience with ultrasonic angioplasty in totally occluded peripheral arteries.
    J Am Coll Cardiol, Vol. 15 (Suppl A), p. 104A, 1990.
  1. Rosenschein, U, Rozenszajn LA, David D, Marboe CC, Rose EA, Watkins JF, Cannon PJ.
    Ultrasonic angioplasty in peripheral vascular disease.
    Eur Heart J, Vol 11 (Suppl), p. 191, 1990.
  1. Rosenschein U, Rozenszajn LA, Rose EA, Watkins JF, Marboe CC, Cannon PJ, Weinstein JS.
    Ultrasonic angioplasty in totally occluded peripheral arteries.
    Circulation, Vol. 82(III), p. 871, 1990.
  1. Watkins, JF, Rose EA, DetWiler P, Fong JC, Sanchez JA, Coppey LJ, Cannon PJ, Rosenschein U.
    Mechanism of ultrasonic angioplasty.
    Circulation, Vol. 82(III), p. 869, 1990.
  1. Rosenschein U, Dick JLR, Haudenschild CC, Topol EJ.
    Does coronary arteriography morphology indicate plaque content?
    J Am Coll Cardiol, Vol. 17 (Suppl A), p. 239A, 1991.
  1. Rosenschein U, DetWiler P, Rose EA, Watkins JF.
    Ultrasonic angioplasty displays elasticity-dependent ablation.
    Eur Heart J, Vol. 12 (Suppl), p. 7, 1991.
  1. Rosenschein U, Guberinich D, Yakubov SJ, Bach DS, Abrams GD, Sonda PL, Topol EJ.
    Shock wave thrombus ablation: a promising non-invasive method for mechanical thrombolysis.
    Circulation, Vol. 84, pp. 11-269, 1992.
  1. Nath CF, Rosenschein U, Muller DWM, Hacker JA, Guberinich D, Ellis SG.
    Heparin monitoring during PTCA: ACT or APTT?
    Circulation, Vol. 84, pp. 11-592, 1992.
  1. Yakubov SJ, Dick RJ, Haudenschild CC, Rosenschien U.
    Deep tissue retrieval with coronary atherectomy is paradoxically associated with less restenosis.
    Circulation, Vol. 84, pp. 11-529, 1992.
  1. Hartnell GG, Saxson FS, Abela GSA, Rosenschein U.
    Coronary ultrasonic thrombus ablation: assessment of a new transcatheter device for coronary thrombolysis.
    Eur Heart J, Vol. 13 (Suppl), p. 14, 1992.
  1. Lincoff AM, Ellis SG, Galeana A, Sigmon KN, Lee KL, Rosenschein U, for the TAMI study group.
    Is a coronary artery with TIMI grade 2 flow “patent”? Outcome in the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) trial.
    Circulation, Vol. 86, pp. 11-268, 1992.
  1. Rosenschein U, Rozenszajn LA, Bernheim J, Frimerman, A, Keren G, Roth D, Laniado S, Miller HI.
    A new Coronary Ultrasound Angioplasty device: Study of acute effects in-vivo.
    Eur Heart J, Vol. 14 (Suppl), pp. Ii-iv, 1993.
  1. Roller M, Perry C, Sutton JM, Grambow D, Kandalwal M, Palacios I, Rosenschein U.
    Urokinase therapy in the Catheterization Laboratory is associated with high rate of bleeding.
    Circulation, Vol. 88, pp. 1-252, 1993.
  1. Rosenschein U, Bernheim J, Frimerman A, Keren G, Roth A, Laniado S,

Miller HI.
Coronary Ultrasound Angioplasty: Study of acute effects in vivo.
Circulation, Vol. 88, pp. 1-546, 1993.

  1. Koifman B, Baron J, Frimerman A, Keren G, Rosenschein U, Laniado S, Miller HI
    Technetium-99m MIBI during PTCA: a new method to assess myocardium at rest.
    Isr J Med Sci Vol. 30, pp188, 1994
  1. Frimerman A, Miller HI, Rosenschein U, RothA, Laniado S, Keren G.
    Mechanism of PTCA in acute coronary syndromes assessed by intravascular ultrasound.
    J Am Coll Cardiol, Vol. 21, p. 404A, 1994.
  1. Miller HI, Frimerman A, Rosenschein U, Laniado S, Keren G.
    Prolonged dilatation improves the results of PTCA – an intravascular ultrasound and angiography study.
    J Am Coll Cardiol, Vol. 21, p. 404A, 1994.
  1. Frimerman A, Miller HI, Rosenschein U, Roth A, Laniado S, Keren G.
    Intravascular ultrasound characteristic as determinant of long term PTCA results in patients with acute myocardial infarction.
    J Invasive Cardiol, Vol. 7, (Suppl C), p. 11C, 1995.
  1. Rosenschein U, Alter A, Rozenszajn LA, Miller HI
    Therapeutic ultrasound inhibits smooth muscle cell migration and adhesion.
    Eur Heart J, Vol 16 (Suppl), p. 229, 1995.

24. Rosenschein U, Miller HI.
Three years of the coronary ultrasound angioplasty experience: from bench testing to clinical trial.
J Invas Cardiol, Vol. 7 (Suppl C), p. 37C, 1995.

  1. Rosenschein U, Alter A, Rozenszajn LA, Miller HI.
    Therapeutic ultrasound inhibits smooth muscle cells migration and adhesion.
    J Invas Cardiol, Vol. 7 (Suppl C), p. 40C, 1995.
  2. Miller HI, Luchansky M, Rosenschein U, Frimerman A, Shefer A,
    Laniado S.
    Changes in stroke volume during acute occolusion of a coronary artery in man.
    J Invas Cardiol, Vol. 7 (Suppl C), p. 44C, 1995.
  1. Rosenschein U, Roth a, Laniado S, Bassan S, Shefer A, Frimerman A, Miller HI.
    Ultrasound thrombolysis in acute myocardial infarction: initial results.
    J Am Coll Cardiol, Vol. 27 (Suppl A), p. 81A, 1996.

28. Rosenschein U, Roth A, Laniado S, Rassin T, Shefer A, Frimerman A, Miller HI.
Ultrasound thrombolysis in acute myocardial infarction: initial results from first clinical experience.
Israel J Med Sci, Vol. 32 (Suppl), p. S6, 1996.

  1. Blum A, Vardinon N, Rosenschein U, Frimerman A, Shefer A,
    Laniado S,
    Miller HI. Coronary artery inflammation – a prolonged phenomenon after successful revascularization.
    Israel J Med Sci, Vol. 32 (Suppl), p. S3, 1996 (Abstr).
  1. Blum A, Vardinon N, Rosenschein U, Frimerman A, Shefer A, Laniado S, Miller HI.
    Characterization of the angina pectoris (AP) syndrome by inflammatory markers.
    Israel J Med Sci, Vol. 32 (Suppl), p. S3, 1996 (Abstr).
  1. Rassin T, Rosenschein U, Frimerman A, Shefer A, Miller HI.
    The utility of rotational atherectomy in complex coronary stenosis unsuitable for balloon angioplasty.
    Israel J Med Sci, Vol. 32 (Suppl), p. S22, 1996 (Abstr).
  1. Rosenschein U, Roth A, Laniado S, Rasin T, Basan S, Miller HI.
    Coronary ultrasound thrombolysis in myocardial infarction: results of the feasibility phase study.
    Circulation (Suppl) 1996; Vol. 94(8):I-86 (Abstr.).
  1. Rosenschein U, Roth A, Laniado S, Rasin T, Basan S, Shefer A, Miller HI.
    Analysis of coronary ultrasound thrombolysis (ACUTE trial) in myocardial infarction: Results of the feasibility phase.
    Eur Heart J, Vol. 17, p.181, 1996.
  1. Alter A, Kinor N, Savion N, Rosenschein U, Rozenszajn LA.
    Immune modulation of vascular SMC proliferation and migration in an in-vitro system.
    J Vascular Res, Vol. 33, p. S1-3, 1996.
  1. Rosenschein U, Rozenszajn LA, Miller HI, Alter A.
    Therapeutic ultrasound induces disorganization of the cytoskeleton and inhibition of smooth muscle cell adhesion and migration.
    J Vascular Res, Vol. 33, p. S1-85, 1996.
  1. Rosenschein U, Eshel, Y, Furman, V, Kerner, E, Laniado, S, Miller HI.
    Focused therapeutic ultrasound is a safe and effective method for non-invasive thrombolysis: results of in vitro studies.
    J Invasive Cardiol, Vol. 9, Suppl C, p 17C, 1997.
  1. Blum A, Weinberg G, Giladi U, Rosenschein U, Pasternak S, Laniado S, Miller HI.
    Anticytomegalovirus (CMV) antibodies – a marker of restenosis.
    J Invasive Cardiol, Vol. 9, Suppl C, p 32C, 1997
  1. Blum A, Weinberg G, Giladi U, Rosenschein U, Pasternak S, Laniado S, Miller HI.
    Anticytomegalovirus (CMV) antibodies and coronary artery disease.
    J Invasive Cardiol, Vol. 9, suppl C, p 35C, 1997.
  1. Blum A, Vardinon N, Kaplan G, Keren G, Rosenschein U, Laniado S, Yust I, Burke M, Miller HI.
    Serum amyloid type A (SAA) – a marker of restenosis.
    J Invasive Cardiol, Vol. 9, Suppl C, p 48C, 1997.
  1. Rosenschein U, Thuesen L, Andersen HR, Laniado S, Miller HI, Hertz I, Haude H, Erbel R.
    Coronary ultrasound thrombolysis in acute myocardial infarction: results from the ACUTE study.
    Circulation Vol. 96, (Suppl), p I-206, 1997.
  1. Agmon Y, Miller HI, Roth A, Rassin T, Frimerman A, Keren G, Laniado S, Rosenschein U.
    Coronary ultrasound thrombolysis in acute myocardial infarction (ACUTE Study): 6 month follow-up of the feasibility phase patients.
    Eur. Heart J, Vol.18, p. 271, 1997.
  2. Rosenschein U, Hertz I, Tenenbaum-Koren E, Thuesen L, Andersen HR, Laniado S, Miller HI, Erbel R.
    Coronary ultrasound thrombolyis in acute myocardial infarction: Results from the ACUTE Study
    J Am Coll Cardiol Vol. 31,pp 192A, 1998.
  1. Muller DWM, Moncur J, Rosenschein U ,Nicklas J.
    Ultrasound Thrombolysis: Ablated Thrombus Does Not Impede Microcirculatory Flow or Impair Regional Left Ventricular Wall Motion.
    Aust NZ Med, Vol. 28, pp 128, 1998.
  1. Miller HI, Rosenschein U, Herz I, Thuesen L, Anderson HR, Laniado S, Erbel.
    Coronary ultrasound thrombolysis in acute myocardial infarction: results from the ACUTE study.

Eur Heart J Vol. 19, pp 398, 1998.

  1. Fajadet J, Erbel R, Rosenschein U. For the Acolysis Registry Group

Coronary ultrasound thrombolysis in occluded saphenous vein grafts: preliminary results.

Eur Heart J Vol.19, pp 393, 1998.

  1. Rosenschein U, Eshel Y, Furman V, Kerner E, Laniado S, Miller HI. Focused non-invasive therapeutic ultrasound thrombolysis is safe and effective in experimental settings.

Eur Heart J Vol. 19, pp 659, 1998.

  1. Rozenszajn LA, Gozdanker N, Ashush H, Shapira H, Rosenschein U, Radnay J.
    Ultrasound irradiation induces apoptosis in HL-60 cells and in normal and pathological blood mononuclear cells.
    British J Haematol Vol. 102, pp 327, 1998.
  1. Fajadet J, Calderon L, Thomas M, Amann F, Desmet W, Ozman F, Gasper J, Erbel R, Hertz I, Gaul G, Miller HI, Rosenschein U.
    Coronary Ultrasound in Acute Coronary Syndromes: the first 100 patients from the Acolysis Registry.
    Circulation Vol. 98, pp I-87, 1998.
  2. Ashush H, Rozenszajn LA, Gozdanker N, Radnay J, Shapira H, Rosenschein U.
    High intensity focus ultrasound induces apoptosis in human leukemic cells. Meeting of the
    Federation of the Israeli Society of Experimental Biology Vol. 105, 1998.
  1. Rosenschein U
    Transcatheter ultrasound thrombolysis – from AMI to saphenous vein grafts and beyond.
    Jap J Interven Cardiol, Vol. 14(1), pp 106, 1999.
  2. Brosh D, Herz I, Laniado S, Miller HI, Rosenschein U

Percutaneous transluminal ultrasound thrombolysis in native coronaries in the setting of acute coronary syndromes.

Int J Cardiol Interven, Vol. 2, pp 39, ‏‏1999

52. Frimerman A, Rosenschein U, Finkelstein A, Bazan S, Keren G, Miller HI

Follow-up angiography for clinical indicatons of patients after stenting reveals patent stent site in most cases

Int J Cardiol Interven, Vol. 2, pp 35, ‏1999

53. Herz I, Erbel R, Miller HI, Gilula Z, Thuesen L, Andersen HR, Laniado S, Agmon Y, Rosenschein U

Improvement of left ventricular function after percutaneous trasnluminal coronary ultrasound thrombolysis in acute myocardial infarction

Int J Cardiol Interven Vol. 2, pp 35, ‏1999.

54. The Acolysis Registry Study Group

Percutaneous transluminal therapy of occluded saphenous vein grafts: Can the challenge be met with ultrasound thrombolysis?

Int J Cardiol Interven Vol. 2, pp 17, ‏1999

55. Rosenschein U

Ultrasound-guided focused ultrasound thrombolysis-The power of bubbles

Int J Cardiol Interven Vol. 2, pp 15, ‏1999.

56. Rosenschein U

Coronary ultrasound thrombolysis-“From Concept to Clinical Reality

Int J Cardiol Interven Vol. 2, pp 15, 1999.

  1. Alter A, Rozenszajn LA, Salzberg S, Hacohen D, Rosenschein U,
    Savion N.
    Changes in smooth muscle cells associated with 2-5A synthetase activity in response to immune system cell signals.

    Thromb Haemost (Aug Suppl); 626, 1999.
  1. Rosenschein U for the ATLAS Trial Investigators.
    Ultrasound thrombolysis and high risk vein graft disease: preliminary core lab data from the ATLAS trial.

    J Isr Heart Soc (Suppl);58, 2000
  1. Ashush H, Blass M, Barda-Saad M, Azimov D, Rozenszajn LA, Rosenschein U.
    Therapeutic ultrasound can induce apoptosis in vitro – a potential role for restenosis prevention?.

    J Isr Heart Soc (Suppl); 60, 2000
  1. Frimerman A, Keren G, Rosenschein U, Finkelstein A, Basan S, Miller HI.
    Clinical parameters and functional tests are not predictive for in-stent restenosis.

    J Cardiovasc Intervent, (Suppl);3, 2003
  1. Ashush H, Firestein F, Elimelech R, Barda-Saad M, Radnay J, Rosenschein U, Rozenszajn LA.
    Therapeutic ultrasound: new strategy of apoptosis induction in malignant hemopoietic cells.

    Acta Hematologica, Vol. 103 (Suppl 1), pp 34, 2000.
  1. Shemesh L, Ashush H, Firestein F, Barda-Saad M, Rosenschein U, Rozenszajn LA.
    Apoptosis induction in human p53 positive cancer cells treated with therapeutic ultrasound.

    Acta Hematalogica, Vol. 103 (Suppl 1), pp 58, 2000.
  1. Miller HI, Frimmerman A, Bazan S, Rosenschein U, Shalman E, Barak C, Dgany E, Leibowitz M.
    Assessment of the distal coronary bed: online analysis using intracoronary pressure measurements.

    Am J Cardiol, pp 106i, 2000
  1. Erbel R, Kuechler R, Miller HI, Herz I, Rosenschein U.
    Ultrasound thrombolysis has a positive effect on restenosis rates in AMI patients.
    Am J Cardiol, pp 95i, 2000
  1. Erbel R, Kuechler R, Miller HI, Herz I, Rosenschein U.
    Therapeutic ultrasound reduces restenosis rates in primary PCI in AMI patients.
    J Am Coll Cardiol, Vol. 37 (suppl), pp70A, 2001.
  1. Rosenschein U, Ashush H, Blass M, Barda-Saad M, Alter A, Firestein F, Rozenszajn LA.
    Therapeutic ultrasound can induce apoptosis in smooth muscle cells: a potential role for restenosis prevention.

    J Am Coll Cardiol, Vol. 37 (Suppl), pp26A, 2001.
  1. Rosenschein U, Ashush H, Blass M, Barda-Saad M, Alter A, Firestein F, Rozenszajn LA, Rechavi G.
    Therapeutic ultrasound and smooth muscle cell functions – a potential role for restenosis prevention.

    J Isr Heart Soc (Suppl), p1, 2001
  1. Rosenschein U, Herz I, Kuechler R, Miller HI, Erbel R.
    Therapeutic ultrasound reduces restenosis rates in primary PCI in AMI patients

    J Isr Heart Soc (Suppl), p18, 2001
  1. Ashush, H., Firestein, F., Shemesh, L., Elimelech, R., Aran, Y., Radnay, J., Shapiro, H., Rosenschein, U. and Rozenszajn, L.A. Ceramide signaling pathway involvement in ultrasound-induced apoptosis.

Exp. Hematol. Vol , pp 29, 2001.

  1. Firestein, F., Elimelech, R., Ashush, H., Shemesh, L., Aran, Y., Radnay, J., Schickler, R., Rosenschein, U. and Rozenszajn, L.A. Apoptosis induction of p53 positive malignant lymphoid cells by ultrasound application.

Exp. Hematol. Vol 29, pp 67, 2001.

  1. Firestein F, Rozenszajn LA,, Shemesh-Darvish L, Elimelech R, Radnay J, Rosenschein U. Apoptosis induction of human malignant lymphoid cells by ultrasound application. Role of mitochondria – caspase pathway activation. “Apoptosis 2003, from signaling pathway to therapeutic tools” Luxemburg, February 2003.
  1. Singh M, Rosenschein U, Kalon KH, Berger PB, Kuntz R, Holmes DR Treatment of Saphenous Vein Bypass Grafts with Ultrasound Trombolysis: A Randomized Trial

J Am Coll Cardiol. Vol 41 (Supp A), pp 43A, 2003

  1. Goldhammer E, Biniamini Y,Rosenschein U, Maor I, anchilevitch A.

Paraoxonase serum activity is reduced by aerobic exercise.

The Annual Meeting of the ESC 8/2004 Munich, Germany.

European Heart Journal. Vol. 25, suppl., p.357-358, 2004.

  1. Bar-Meir E, Zeina AR, Blinder J , Rosenschein U

Assessment of Coronary Artery Bypass Grafts by Cardiac Computed Tomography Angiography.

IMAJ ;Vol 7:275-276, 2005.

  1. Goldhammer E, Maor I, Rosenschein U, Lanir A, Sagiv M.

B-Type Natriuretic Peptide Response to Aerobic Exercise Test Compared

to Strength Testing in Patients with Left Ventricular Dysfunction.

Spring Meeting Leuven ,April 7-10, 2005.

  1. Sharif D, Sharif-Rasslan A, Shefer A, Makhoul N, Hassan A, Rosenschein U.

Left Anterior Descending Coronary Artery Velocity Profiles Change During

Follow up After Primary Angioplasty in Acute Anterior Myocardial Infarction

and Predict Recovery of Left Ventricular Function.

Circulation; Vol 112:17,2005.

77. Zaid G, Tanchilevitch A, Gropper A, Rivlin E, Lanir A, Rosenschein U,

Goldhammer E.

Diagnostic accuracy of Serum B-type Natriuretic Peptide for Myocardial

Ischemia Detection During Exercise Testing with Spect Perfusion Imaging.

Int J Cardiol, Vol 25;117(2):157-164,2007

78. Hammoud M, Makhoul N, Sharif D, Shefer A, Hassan A ,Storch S,

Loberman Z, Rosenschein U.

Screening, diagnosis and treatment of renal artery stenosis by

Percutaneous Transluminal Renal Angioplasty (PTRA) with stenting, the

Haifa experience.

WCC- Barcelona,September 2006.

79. M. Hammoud, D. Sharif, Rosenschein U.

Risk factors, psychosocial factors, clinical manifestation and outcome of

very young adults presented with acute myocardial infarction, a single

center experience.

WCC-Barcelona, September 2006.

80. Zeina AR., Blinder J.,Rosenschein U.,Makhoul N., Barmeir E.

Left main coronary artery disease: Should patients undergo coronary CT

Angiography befor bypass grafting surgery?

ISRA, Nov.Tel-Aviv, 2006.

81. Goldhammer E, Zaid G, Rivlin E, Gropper R, Lanir A, Rosenschein U.

The contribution of serum B-type natriuretic peptide to the diagnostic

accuracy of myocardial ischemia detection during exercise testing with

SPECT perfusion imaging.

Journal of Nuclear Cardiology, Vol 14:2,2007

82. Goldhammer E, Zeina AR, Ben Moshe Y, Zaid G, Rivlin E, Maor I,

Bar Meir E, Rosenschein U.

Endothelin-1 is associated with the presence of soft plaques in

asymptomatic subjects, as diagnosed by 64-row multidetector computed

tomography.

Journal of Nuclear Cardiology, Vol 14:2,2007

83. Hammoud H, Sharif D, U Rosenschein.

Percutaneous Renal Artery Angioplasty for Renal Artery Stenosis

Reduces the Incidences of Flash Pulmonary Edema and Hospitalization

Rate for Acute Heart Failure.

European Society of Cardiology, Vienna September 2007

84. Scheinert D, Rosenschein U, Ulrich M, Bräunlich S, Schmidt A,

A New Modular Embolic Protection System; First In Man Experience.

PCR, Barcelona 2009.

Participation in organizing conferences

Session Panel Member Transcatheter Cardiovascular Therapeutics
Washington, DC, September 1997

Interviewee American College of Cardiology (ACCEL)

Taped during the AHA

Washington, DC, November 13-17, 1988

Session Chairman Endovascular Therapy Course Coronary and Peripheral
Paris, France, May 1998

Session Guest Animator Endovascular Therapy Course Coronary and Peripheral
Paris, France, May 1998

Course Co-Organizer & New treatment modalities of coronary thrombus
Co Chairman Milan, Italy, June 1998.

Case Moderator Transcatheter Cardiovascular Therapeutics,

Washington DC, USA, Oct 1998

Discussant Transcatheter Cardiovascular Therapeutics,

Washington DC, USA, Oct 1998

Case Moderator Transcatheter Cardiovascular Therapeutics,

Washington DC, USA, October 1999

Discussant Transcatheter Cardiovascular Therapeutics,

Washington DC, USA, October 1999

Case Moderator American College of Cardiology 49th Annual Session (ACCIS 2000)
Anaheim, CA, March 2000

Chairman & Organizer PCI in Thrombus-Rich Lesions Symposium
PCR Paris, France, May 2000

Case Moderator Transcatheter Cardiovascular Therapeutics,

Washington DC, USA, October 2000

Discussant Transcatheter Cardiovascular Therapeutics,

Washington DC, USA, October 2000

Co- Chair4th International Meeting on Interventional Cardiology: Frontiers in Interventional Cardiology
London, June 2001

Chairman 4th International Meeting on Interventional Cardiology: Frontiers in Interventional Cardiology

Discussant Transcatheter Cardiovascular Therapeutics,

Washington DC, USA, October 2001

Live Case Discussant Transcatheter Cardiovascular Therapeutics,

Washington DC, USA, October 2001

Interviewee American College of Cardiology (ACCEL)

Taped during the AHA Anaheim CA, November

2001(Vol. 54, No 2, Feb 2002)

Session Chairman European Society of Cardiology

Embolic Protection Devices

Berlin, Germany September, 2002

Session Chairman Transcatheter Cardiovascular Therapeutics,

Washington DC, USA September 2002

Founder & Co Chairman Yearly debate Meeting

“Point Counter Point”,

Tel Aviv University. 2002-Present.

Symposia Chairman Embolic Protection Devices

European Society of Cardiology

Berlin, Germany September, 2002

Session Chairman Complication- my worst nightmare

Transcatheter Cardiovascular Therapeutics,

Washington DC, USA September 2002

Symposia Chairman Evolving Role of Distal Protection

American College of Cardiology

Chicago USA March 2003

Poster Abstract Moderator Transcatheter Cardiovascular Therapeutics,

Washington DC, USA, September, 2003

Symposia-Chairman Hematopoiesis:From Basic Research to Tissue

Engineering.

February 2004. Bar-Ilan University.

Symposia-Co-Chair Adjunctive Mechanical Therapy

American College of Cardiology

New-Orleans USA March 2004.

Co-Chair The 53rd Annual Meeting of Israel Heart Association, Tel-Aviv, April 2006.

Chairman Technology parade

Interventional Accessory

Devices

ICI Tel-Aviv, December 2006.

Scientific Committee International Sonothrombolysis Conference

Mannheim/Heidelberg Germany,July 4-5,2008

Discussant Embolic Protection and Thrombectomy Symposia.

Transcatheter Cardiovascular Therapeutics

Washington, October 2008.

Chairman & Organising The first D.Dan and Betty Kahn ,

Commitee University of Michigan– Technion, Collaborative

Cardiovascular Research Ann Arbor, Michigan; October 4, 2011

Symposium

ChairmanRenal Denervation,

Innovations in Cardiovascular Interventions,

Tel-Aviv, December 2012.

Organizing Committee The 2nd D.Dan and Betty Kahn ,

University of Michigan– Technion,

Electricity and Sugar in the Heart. Technion,

Haifa, December 6, 2012

Organizing Committee Israeli Society for Medical and Biological

Engineering (ISMBE) Biomedical Engineering

2013.